Identification of linear epitopes and their major role in the immunoglobulin E-binding capacity of tropomyosin from <i>Alectryonella plicatula</i>-Reference-Cited by-同舟云学术

Identification of linear epitopes and their major role in the immunoglobulin E-binding capacity of tropomyosin from Alectryonella plicatula

Published:2022 Issue:17 Volume:13 Page:9078-9090
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Ji Nai-Ru¹,Han Xin-Yu¹,Yu Chen-Chen¹,He Xin-Rong¹,Rao Shi-Tao²,Huan Fei¹,Liu Hong¹,Chen Gui-Xia³,Cao Min-Jie¹,Liu Guang-Ming¹^ORCID

Affiliation:

1. College of Ocean Food and Biological Engineering, Xiamen Key Laboratory of Marine Functional Food, Fujian Provincial Engineering Technology Research Center of Marine Functional Food, Jimei University, Xiamen, Fujian 361021, China

2. School of Medical Technology and Engineering, Fujian Medical University, Fuzhou, Fujian 350004, China

3. Women and Children's Hospital Affiliated to Xiamen University, Xiamen, Fujian 361003, China

Abstract

The allergen TM was purified from Alectryonella plicatula; the sequence was cloned. Linear epitopes played a major role in IgE-binding capacity of ATM. Nine linear epitopes were verified. L-ATM-2 was the key epitope to bind with IgE; L-ATM-5 and L-ATM-7 were most conservative in shellfish.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Xiamen Municipal Bureau of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO01713J

Reference42 articles.

1. Food Allergy