Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways-Reference-Cited by-同舟云学术

Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways

Published:2019 Issue:42 Volume:10 Page:9708-9720
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Simpson Daniel H.¹²³⁴,Hapeshi Alexia⁵²³⁴,Rogers Nicola J.¹²³⁴^ORCID,Brabec Viktor⁶⁷⁸⁹^ORCID,Clarkson Guy J.¹²³⁴,Fox David J.¹²³⁴^ORCID,Hrabina Ondrej⁶⁷⁸⁹¹⁰,Kay Gemma L.⁵²³⁴,King Andrew K.¹²³⁴,Malina Jaroslav⁶⁷⁸⁹^ORCID,Millard Andrew D.⁵²³⁴,Moat John¹¹²³⁴,Roper David I.¹¹²³⁴,Song Hualong¹²³⁴^ORCID,Waterfield Nicholas R.⁵²³⁴,Scott Peter¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Warwick

3. Coventry

4. UK

5. Warwick Medical School

6. The Czech Academy of Sciences

7. Institute of Biophysics

8. CZ-61265 Brno

9. Czech Republic

10. Department of Biophysics

11. School of Life Sciences

Abstract

Iron-based self-assembled optically pure compounds mimic the mechanisms of small peptides, according to biophysical, genomic, transcriptomic and other analyses.

Funder

Engineering and Physical Sciences Research Council

University of Warwick

Leverhulme Trust

Warwick Medical School

Grantová Agentura České Republiky

China Scholarship Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC03532J

Reference85 articles.

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2. World Health Organisation , No Time to Wait: securing the future from drug-resistant infections , UN Interagency Coordination Group on Antimicrobial Resistance , 2019 , https://www.who.int/antimicrobial-resistance/interagency-coordination-group/final-report/en/

3. The role of cationic antimicrobial peptides in innate host defences

4. Antimicrobial peptides of multicellular organisms

5. Molecular mechanisms of membrane targeting antibiotics

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