Evaluation of the Antimicrobial Activity in Host-Mimicking Media and In Vivo Toxicity of Antimicrobial Polymers as Functional Mimics of AMPs

Author:

Garcia Maset Ramón1ORCID,Hapeshi Alexia2ORCID,Hall Stephen23ORCID,Dalgliesh Robert M.3ORCID,Harrison Freya4ORCID,Perrier Sébastien125ORCID

Affiliation:

1. Warwick Medical School, University of Warwick, Coventry CV4 7AL, U.K.

2. Department of Chemistry, University of Warwick, Coventry CV4 7AL, U.K.

3. ISIS Neutron and Muon Source, Rutherford Appleton Laboratory, Didcot OX11 0DE, U.K.

4. School of Life Sciences, University of Warwick, Coventry CV4 7AL, U.K.

5. Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia

Funder

Medical Research Council

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

Reference70 articles.

1. Antimicrobial resistance. World Health Organization (WHO), 2021. https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance (accessed 10 Nov, 2021).

2. Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis

3. Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

4. Antibiotics in the clinical pipeline at the end of 2015

5. Antimicrobial peptides

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