Weak C–H acids as protonophores can carry hydrogen ions through lipid membranes and mitochondria: a case of o-carborane-Reference-Cited by-同舟云学术

Weak C–H acids as protonophores can carry hydrogen ions through lipid membranes and mitochondria: a case of o-carborane

Published:2016 Issue:24 Volume:18 Page:16476-16482
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Rokitskaya Tatyana I.¹²³⁴,Khailova Ljudmila S.¹²³⁴,Makarenkov Anton V.⁵⁶⁷⁴,Ol'shevskaya Valentina A.⁵⁶⁷⁴,Kalinin Valery N.⁵⁶⁷⁴,Antonenko Yuri N.¹²³⁴

Affiliation:

1. Belozersky Institute of Physico-Chemical Biology

2. Lomonosov Moscow State University

3. Moscow 119899

4. Russian Federation

5. Nesmeyanov Institute of Organoelement Compounds

6. Russian Academy of Sciences

7. Moscow

Abstract

ortho-Carborane (1,2-C₂B₁₀H₁₂) was found to be a carrier of protons in lipid membranes and mitochondria, suggesting that this dicarborane can reversibly release hydrogen ions and diffuse through the membrane.

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2016/CP/C6CP02581A

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