Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction-Reference-Cited by-同舟云学术

Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction

Published:2019 Issue:19 Volume:10 Page:5056-5063
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Iegre Jessica¹²³⁴^ORCID,Brear Paul⁵²³⁴^ORCID,Baker David J.⁶⁷⁸³⁴,Tan Yaw Sing⁹¹⁰¹¹,Atkinson Eleanor L.¹²³⁴,Sore Hannah F.¹²³⁴,O' Donovan Daniel H.¹²⁸³⁴^ORCID,Verma Chandra S.⁹¹⁰¹¹¹³¹⁴^ORCID,Hyvönen Marko⁵²³⁴^ORCID,Spring David R.¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. University of Cambridge

3. Cambridge

4. UK

5. Department of Biochemistry

6. Discovery Sciences

7. IMED Biotech Unit

8. AstraZeneca

9. Bioinformatics Institute

10. Agency for Science, Technology and Research (A*STAR)

11. Singapore 138671

12. Oncology, IMED Biotech Unit

13. Department of Biological Sciences

14. National University of Singapore

Abstract

This work describes the efficient development of functionalised, cell-permeable, and stable peptide inhibitors of the protein–protein interaction of CK2.

Funder

Biotechnology and Biological Sciences Research Council

FP7 Ideas: European Research Council

Engineering and Physical Sciences Research Council

Wellcome Trust

Royal Society

Medical Research Council

Agency for Science, Technology and Research

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry