Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1

Author:

Fader Lee D.1,Malenfant Eric1,Parisien Mathieu1,Carson Rebekah1,Bilodeau François1,Landry Serge1,Pesant Marc1,Brochu Christian1,Morin Sébastien1,Chabot Catherine1,Halmos Ted1,Bousquet Yves1,Bailey Murray D.1,Kawai Stephen H.1,Coulombe René1,LaPlante Steven1,Jakalian Araz1,Bhardwaj Punit K.1,Wernic Dominik1,Schroeder Patricia1,Amad Ma’an1,Edwards Paul1,Garneau Michel1,Duan Jianmin1,Cordingley Michael1,Bethell Richard1,Mason Stephen W.1,Bös Michael1,Bonneau Pierre1,Poupart Marc-André1,Faucher Anne-Marie1,Simoneau Bruno1,Fenwick Craig1,Yoakim Christiane1,Tsantrizos Youla1

Affiliation:

1. Research and Development, Boehringer Ingelheim (Canada) Ltd., 2100 Cunard Street, Laval, Québec H7S 2G5, Canada

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference28 articles.

1. World Health Organization. Factsheet No. 360, updated June30, (2013.http://www.who.int/mediacentre/factsheets/fs360/en/index.html(accessed July 14, 2013) .

2. Declining Morbidity and Mortality among Patients with Advanced Human Immunodeficiency Virus Infection

3. Adverse effects of antiretroviral therapy

4. Grade 4 Events Are as Important as AIDS Events in the Era of HAART

5. HIV Drug Resistance

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