Copper-catalyzed cyanothiolation to incorporate a sulfur-substituted quaternary carbon center-Reference-Cited by-同舟云学术

Copper-catalyzed cyanothiolation to incorporate a sulfur-substituted quaternary carbon center

Published:2017 Issue:10 Volume:8 Page:7047-7051
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Huang Yubing¹²³⁴⁵,Li Xianwei¹²³⁴⁵,Wang Xu¹²³⁴⁵,Yu Yue¹²³⁴⁵,Zheng Jia¹²³⁴⁵,Wu Wanqing¹²³⁴⁵,Jiang Huanfeng¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Functional Molecular Engineering of Guangdong Province

2. School of Chemistry and Chemical Engineering

3. South China University of Technology

4. Guangzhou 510640

5. China

Abstract

A copper-catalyzed cyanothiolation of N-tosylhydrazones with thiocyanates to generate α-arylthioalkanenitriles bearing sulfur-substituted quaternary carbon center atoms has been achieved.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC02867A

Reference55 articles.

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4. Nitrile-Containing Pharmaceuticals: Efficacious Roles of the Nitrile Pharmacophore

5. Strategies for the Design of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors: Lessons from the Development of Seven Representative Paradigms

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