A new enantioselective synthesis of antiobesity drug lorcaserin-Reference-Cited by-同舟云学术

A new enantioselective synthesis of antiobesity drug lorcaserin

Published:2019 Issue:43 Volume:43 Page:16876-16880
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Ghotekar Ganesh S.¹²³⁴⁵,More Devidas A.¹²³⁴⁵,Nalla Viswanadh¹²³⁴⁵,Muthukrishnan M.¹²³⁴⁵^ORCID

Affiliation:

1. Division of Organic Chemistry

2. CSIR-National Chemical Laboratory

3. Pune 411008

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

Abstract

A simple and efficient enantioselective synthesis of anti-obesity drug lorcaerin starting from easily accessible 3-chlorostyrene oxide has been described for the first time employing hydrolytic kinetic resolution as a source of chirality.

Funder

Council of Scientific and Industrial Research, India

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NJ/C9NJ04234B

Reference27 articles.

1. Oxidative Stress in Obesity: A Critical Component in Human Diseases

2. A Positive Allosteric Modulator of the Serotonin 5-HT2C Receptor for Obesity

3. The Expanded Biology of Serotonin

4. Anti-Obesity Drugs: A Review about Their Effects and Safety

5. Novel anti-obesity drugs and plasma lipids

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