Osteon-mimetic 3D nanofibrous scaffold enhances stem cell proliferation and osteogenic differentiation for bone regeneration-Reference-Cited by-同舟云学术

Osteon-mimetic 3D nanofibrous scaffold enhances stem cell proliferation and osteogenic differentiation for bone regeneration

Published:2022 Issue: Volume: Page:
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Song Ting¹²,Zhou Jianhua¹²³^ORCID,Shi Ming¹²,Xuan Liuyang¹²,Jiang Huamin¹²,Lin Zefeng⁴⁵,Li Yan¹²³^ORCID

Affiliation:

1. School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 510006, China

2. Guangdong Provincial Key Laboratory of Sensor Technology and Biomedical Instrument, Sun Yat-sen University, Guangzhou 510006, China

3. School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China

4. Department of Orthopedics, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou 510010, China

5. Guangdong Key Laboratory of Orthopedic Technology and Implant Materials, Guangzhou 510010, China

Abstract

Bilayer nanofibrous membranes spontaneously deforming from 2D into 3D structure regulate cell morphology and lamin-A expression to promote proliferation and osteogenic differentiation of rADSCs, which shows a great potential to repair bone defect.

Funder

Shenzhen Fundamental Research Program

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D1BM01489G

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