Acid-promoted rapid solvent-free access to substituted 1,4-dihydropyridines from β-ketothioamides-Reference-Cited by-同舟云学术

Acid-promoted rapid solvent-free access to substituted 1,4-dihydropyridines from β-ketothioamides

Published:2016 Issue:26 Volume:6 Page:21535-21539
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Ming¹²³⁴⁵,Sun Ke-Na¹²³⁴⁵,Wen Li-Rong¹²³⁴⁵

Affiliation:

1. State Key Laboratory Base of Eco-Chemical Engineering

2. College of Chemistry and Molecular Engineering

3. Qingdao University of Science and Technology

4. Qingdao 266042

5. P. R. China

Abstract

1,4-Dihydropyridines were synthesized via a tandem reaction of β-ketothioamides with aldehydes and β-enaminonitriles by AcOH as a promoter within 5 min.

Funder

Natural Science Foundation of Shandong Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA26931H

Reference50 articles.

1. Recent advances in the chemistry of dihydropyridines

2. 1,4-Dihydropyridine Scaffold in Medicinal Chemistry, The Story So Far And Perspectives (Part 2): Action in Other Targets and Antitargets

3. A small-molecule screen in C. elegans yields a new calcium channel antagonist

4. Synthesis and SAR of b-Annulated 1,4-Dihydropyridines Define Cardiomyogenic Compounds as Novel Inhibitors of TGFβ Signaling

5. Cystic Fibrosis: A New Target for 4-Imidazo[2,1-b]thiazole-1,4-dihydropyridines

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