Synthesis and SAR of b-Annulated 1,4-Dihydropyridines Define Cardiomyogenic Compounds as Novel Inhibitors of TGFβ Signaling-Reference-Cited by-同舟云学术

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Synthesis and SAR of b-Annulated 1,4-Dihydropyridines Define Cardiomyogenic Compounds as Novel Inhibitors of TGFβ Signaling

Published:2012-11-06 Issue:22 Volume:55 Page:9946-9957
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Schade Dennis¹²³,Lanier Marion¹³,Willems Erik²³,Okolotowicz Karl¹,Bushway Paul²,Wahlquist Christine²,Gilley Cynthia¹,Mercola Mark²³,Cashman John R.¹³

Affiliation:

1. Human BioMolecular Research Institute, 5310 Eastgate Mall, San Diego, California 92121-2804, United States

2. Sanford-Burnham Medical Research Institute, 10901 North Torrey Pines Road, La Jolla, California 92037, United States

3. ChemRegen Inc., 11171 Corte Cangrejo, San Diego, California 92130, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm301144g

Reference30 articles.

1. A Chemical Biology Approach to Myocardial Regeneration

2. Natural and Synthetic Regulators of Embryonic Stem Cell Cardiogenesis

3. Small Molecule-Mediated TGF-β Type II Receptor Degradation Promotes Cardiomyogenesis in Embryonic Stem Cells

4. Hexahydrochinolinone mit calciummodulatorischem Effekt - Synthese und pharmakologische Wirkung

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