Green approaches to late-stage fluorination: radiosyntheses of 18F-labelled radiopharmaceuticals in ethanol and water-Reference-Cited by-同舟云学术

Green approaches to late-stage fluorination: radiosyntheses of 18F-labelled radiopharmaceuticals in ethanol and water

Published:2015 Issue:79 Volume:51 Page:14805-14808
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Stewart Megan N.¹²³⁴⁵,Hockley Brian G.⁶⁷⁸⁴⁵,Scott Peter J. H.¹²³⁴⁵

Affiliation:

1. Department of Medicinal Chemistry

2. College of Pharmacy

3. The University of Michigan

4. Ann Arbor

5. USA

6. Division of Nuclear Medicine

7. Department of Radiology

8. The University of Michigan Medical School

Abstract

Green strategies for late-stage fluorination with ¹⁸F, in which ethanol and water are the only solvents used throughout the entire radiolabeling process, have been developed and applied to the radiosyntheses of a range of radiopharmaceuticals commonly employed in clinical PET imaging.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC05919D

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