α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction-Reference-Cited by-同舟云学术

α-Hydroxy acid as an aldehyde surrogate: metal-free synthesis of pyrrolo[1,2-a]quinoxalines, quinazolinones, and other N-heterocycles via decarboxylative oxidative annulation reaction

Published:2020 Issue:61 Volume:10 Page:37202-37208
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Viji Mayavan¹²³⁴⁵^ORCID,Vishwanath Manjunatha¹²³⁴⁵^ORCID,Sim Jaeuk¹²³⁴⁵,Park Yunjeong¹²³⁴⁵,Jung Chanhyun¹²³⁴⁵,Lee Seohu¹²³⁴⁵,Lee Heesoon¹²³⁴⁵,Lee Kiho¹⁶⁷⁵,Jung Jae-Kyung¹²³⁴⁵^ORCID

Affiliation:

1. College of Pharmacy

2. Medicinal Research Center (MRC)

3. Chungbuk National University

4. Cheongju 28160

5. Republic of Korea

6. Korea University

7. Sejong 30019

Abstract

A TBHP mediated, metal-free approach for the synthesis of quinoxalines, quinazolinones, and indolo quinoxaline was developed from alpha hydroxy acids via decarboxylation followed by condensation.

Funder

National Research Foundation of Korea

Ministry of Education

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA07093A

Reference125 articles.

1. Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2

2. New ferrocenic pyrrolo[1,2-a]quinoxaline derivatives: Synthesis, and in vitro antimalarial activity – Part II