Electrochemical oxidative dehydrogenative annulation of 1-(2-aminophenyl)pyrroles with cleavage of ethers to synthesize pyrrolo[1,2-a]quinoxaline derivatives

Author:

Sun Fengkai1,Miao Man1,Li Wenxue1,Lan Xiao-Bing1,Yu Jian-Qiang1ORCID,Zhang Jian12ORCID,An Zhenyu1ORCID

Affiliation:

1. College of Pharmacy, Ningxia Characteristic Traditional Chinese Medicine Modern Engineering Research Center, Ningxia Medical University, Yinchuan, Ningxia Hui Autonomous Region, China

2. State Key Laboratory of Oncogenes and Related Genes, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

Abstract

In this study, we present an electrochemical approach for the synthesis of pyrrolo[1,2-a]quinoxaline derivatives from 1-(2-aminophenyl)pyrroles and ethers in simple homemade undivided cells.

Funder

Natural Science Foundation of Ningxia Province

Ningxia Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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