Modified multicomponent Biginelli–Atwal reaction towards a straightforward construction of 5,6-dihydropyrimidin-4-ones-Reference-Cited by-同舟云学术

Modified multicomponent Biginelli–Atwal reaction towards a straightforward construction of 5,6-dihydropyrimidin-4-ones

Published:2015 Issue:57 Volume:5 Page:46267-46271
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Pair Etienne¹²³⁴⁵,Levacher Vincent¹²³⁴⁵,Brière Jean-François¹²³⁴⁵

Affiliation:

1. Normandie Univ

2. COBRA

3. UMR 6014 et FR 3038

4. Univ Rouen

5. INSA Rouen

Abstract

A modified multicomponent Biginelli condensation with Meldrum's acid affords a straightforward access to 5,6-dihydropyrimidin-4-ones through a domino Knoevenagel-aza-Michael-Cyclocondensation (KaMC) reaction.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA08792A

Reference46 articles.

1. Biologically active dihydropyrimidones of the Biginelli-type — a literature survey

2. The Generation of Dihydropyrimidine Libraries Utilizing Biginelli Multicomponent Chemistry

3. Solid- and solution-phase synthesis of bioactive dihydropyrimidines

4. Asymmetric Organocatalytic Biginelli Reactions: A New Approach To Quickly Access Optically Active 3,4-Dihydropyrimidin-2-(1H)-ones

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