Carbene-catalyzed selective addition of isothioureas to enals for access to sulphur-containing 5,6-dihyropyrimidin-4-ones-Reference-Cited by-同舟云学术

Carbene-catalyzed selective addition of isothioureas to enals for access to sulphur-containing 5,6-dihyropyrimidin-4-ones

Published:2021 Issue:4 Volume:8 Page:743-747
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Maiti Rakesh¹²³⁴⁵,Xu Jun¹²³⁴⁵,Yan Jia-Lei¹²³⁴⁵^ORCID,Mondal Bivas¹²³⁴⁵,Yang Xing¹²³⁴⁵,Chai Huifang⁶⁷⁸,Hao Lin¹²³⁴⁵^ORCID,Jin Zhichao⁹¹⁰¹¹⁷⁸,Chi Yonggui Robin¹²³⁴⁵^ORCID

Affiliation:

1. Division of Chemistry & Biological Chemistry

2. School of Physical & Mathematical Science

3. Nanyang Technological University

4. Singapore 637371

5. Singapore

6. Guizhou University of Traditional Chinese Medicine

7. Guiyang 550025

8. China

9. Key Laboratory of Green Pesticide and Agriculture Bioengineering

10. Ministry of Education

11. Guizhou University

Abstract

A carbene-catalyzed highly regioselective and enantioselective 1,4-addition reaction between isothioureas and enals has been achieved under oxidative conditions.

Funder

National Research Foundation Singapore

Ministry of Education - Singapore

Agency for Science, Technology and Research

Nanyang Technological University

National Natural Science Foundation of China

Guizhou Science and Technology Department

Project 211

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry