One-pot strategy of copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles-Reference-Cited by-同舟云学术

One-pot strategy of copper-catalyzed synthesis of 1,2-disubstituted benzimidazoles

Published:2017 Issue:27 Volume:15 Page:5811-5819
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Xie Caixia¹²³⁴,Han Xushuang¹²³⁴,Gong Jian¹²³⁴,Li Danyang¹²³⁴,Ma Chen¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry and Chemical Engineering

2. Shandong University

3. Jinan

4. P R China

5. State Key Laboratory of Bioactive Substance and Function of Natural Medicines

Abstract

A simple, one-pot and copper-catalyzed coupling reaction for the construction of 1,2-disubstituted benzimidazole derivatives is described. A low-cost copper salt and a weak base, K₃PO₄, were utilized in this reaction. A variety of 1,2-disubstituted benzimidazoles were obtained in moderate to excellent yields.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00945C

Reference45 articles.

1. Synthesis and investigation of novel benzimidazole derivatives as antifungal agents

2. Synthesis of benzimidazole-based 1,3,4-oxadiazole-1,2,3-triazole conjugates as glycogen synthase kinase-3β inhibitors with antidepressant activity in in vivo models

3. Carbon nanotube-based QuEChERS extraction and enhanced product ion scan-assisted confirmation of multi-pesticide residue in dried tangerine peel

4. Dimeric 1,3-Phenylene-bis(piperazinyl benzimidazole)s: Synthesis and Structure–Activity Investigations on their Binding with Human Telomeric G-Quadruplex DNA and Telomerase Inhibition Properties

5. Antiviral drugs for cytomegalovirus diseases

Cited by 28 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Electrochemical Sensing of Bisphenol A Using Metal Organic Framework/Quantum Dot Composite Modified Gold Electrode;ChemElectroChem;2024-09-05

2. Recent advances in the synthesis of benzimidazolo[2,1-a]isoquinoline-6(5H)-one derivatives from N-methylacryloyl-2-arylbenzimidazoles;Tetrahedron;2024-06

3. Copper-Catalyzed Coupling between ortho-Haloanilines and Lactams/Amides: Synthesis of Benzimidazoles and Telmisartan;The Journal of Organic Chemistry;2024-04-02

4. Optimized Synthesis of the Key Intermediate of Telmisartan via the Cyclization of 2-Bromoarylamine with n-Butyronitrile;Organic Process Research & Development;2023-11-06

5. Nano Cr(III) Schiff-base complex supported on magnetic Fe3O4@SiO2: efficient, heterogeneous, and recoverable nanocatalyst for chemoselective synthesis of 1,2-disubstituted benzimidazoles;Monatshefte für Chemie - Chemical Monthly;2023-07-21