Synthesis of benzimidazole-based 1,3,4-oxadiazole-1,2,3-triazole conjugates as glycogen synthase kinase-3β inhibitors with antidepressant activity in in vivo models-Reference-Cited by-同舟云学术

Synthesis of benzimidazole-based 1,3,4-oxadiazole-1,2,3-triazole conjugates as glycogen synthase kinase-3β inhibitors with antidepressant activity in in vivo models

Published:2016 Issue:49 Volume:6 Page:43345-43355
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tantray Mushtaq A.¹²³⁴⁵,Khan Imran¹²³⁴⁵,Hamid Hinna¹²³⁴⁵,Alam Mohammad Sarwar¹²³⁴⁵,Dhulap Abhijeet⁶⁷⁵,Kalam Abul⁸⁹³⁴⁵

Affiliation:

1. Department of Chemistry

2. Faculty of Science

3. Jamia Hamdard (Hamdard University)

4. New Delhi 110062

5. India

6. CSIR – Unit for Research and Development of Information Products (URDIP)

7. Pune 411038

8. Department of Pharmacology

9. Faculty of Pharmacy

Abstract

Synthesized benzimidazole based 1,3,4-oxadiazole-1,2,3-triazole conjugates were found to inhibit GSK-3β activityin vitroand exhibit antidepressant-like activity inin vivostudies.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA07273A

Reference43 articles.

1. Molecular cloning and expression of glycogen synthase kinase-3/factor A.

2. Selective loss of glycogen synthase kinase-3α in birds reveals distinct roles for GSK-3 isozymes in tau phosphorylation

3. Glycogen synthase kinase 3: A point of convergence for the host inflammatory response

4. Regulation of protein stability by GSK3 mediated phosphorylation

5. FXR1P is a GSK3β substrate regulating mood and emotion processing

Cited by 38 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Quinoline-1,2,3-triazole hybrids: Design, synthesis, antimalarial and antimicrobial evaluation;Journal of Molecular Structure;2024-11

2. Benzimidazole–Oxadiazole Hybrids—Development in Medicinal Chemistry: An Overview;Chemical Biology & Drug Design;2024-08

3. Synthetic approach to new 2H-benzo[b] [1,4]oxazin-3-one derivatives containing 1,2,3-triazole by click chemistry;Tetrahedron;2024-08

4. Exploring the versatility of sulfur-containing heterocyclic metal complexes: Application in medical and prospects of visible-light-driven photocatalysis;Journal of Inorganic Biochemistry;2024-08

5. Efficient synthetic strategies for fused pyrimidine and pyridine derivatives: A review;Journal of Heterocyclic Chemistry;2024-07-17