Dimeric 1,3-Phenylene-bis(piperazinyl benzimidazole)s: Synthesis and Structure–Activity Investigations on their Binding with Human Telomeric G-Quadruplex DNA and Telomerase Inhibition Properties-Reference-Cited by-同舟云学术

Dimeric 1,3-Phenylene-bis(piperazinyl benzimidazole)s: Synthesis and Structure–Activity Investigations on their Binding with Human Telomeric G-Quadruplex DNA and Telomerase Inhibition Properties

Published:2012-03-27 Issue:7 Volume:55 Page:2981-2993
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Jain Akash K¹,Paul Ananya¹,Maji Basudeb¹,Muniyappa K.²,Bhattacharya Santanu¹³

Affiliation:

1. Department of Organic Chemistry, Indian Institute of Science, Bangalore 560012, India

2. Department of Biochemistry, Indian Institute of Science, Bangalore 560012, India

3. Chemical Biology Unit, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore 560012, India

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm200860b

Reference75 articles.

1. Conservation of the human telomere sequence (TTAGGG)n among vertebrates.

2. Characterization of Structure and Stability of Long Telomeric DNA G-Quadruplexes

3. Structure and function of telomeres

4. G‐Quadruplex DNA Structures and Organic Chemistry: More Than One Connection

5. Interaction of G-Quadruplexes with Nonintercalating Duplex-DNA Minor Groove Binding Ligands

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