Small lectin ligands as a basis for applications in glycoscience and glycomedicine

Author:

Murphy Paul V.123ORCID,Dhara Ashis12ORCID,Fitzgerald Liam S.123ORCID,Hever Eoin1,Konda Saidulu1ORCID,Mandal Kishan1

Affiliation:

1. School of Biological and Chemical Sciences, Galway, H91TK33, Ireland

2. SSPC, SFI Research Centre for Pharmaceuticals, Galway, H91TK33, Ireland

3. CÚRAM, SFI Research Centre for Medical Devices, University of Galway, University Road, Galway, H91TK33, Ireland

Abstract

Understanding lectin–ligand interaction inspires synthesis of glycomimetic and glycocluster ligands for applications.

Funder

Science Foundation Ireland

Irish Research Council

Publisher

Royal Society of Chemistry (RSC)

Reference150 articles.

1. A.Varki and S.Kornfeld Historical , Background and Overview , in Essentials of Glycobiology , ed. A. Varki , R. D. Cummings , J. D. Esko , P. Stanley , G. W. Hart , M. Aebi , D. Mohnen , T. Kinoshita , N. H. Packer , J. H. Prestegard , R. L. Schnaar and P. H. Seeberger , Cold Spring Harbor Laboratory Press , Cold Spring Harbor , 4th edn, 2022 . ch. 1

2. M. E.Taylor , K.Drickamer , A.Imberty , Y.van Kooyk , R. L.Schnaar , M. E.Etzler and A.Varki , Discovery and Classification of Glycan-Binding Proteins , in Essentials of Glycobiology , ed. A. Varki , R. D. Cummings , J. D. Esko , P. Stanley , G. W. Hart , M. Aebi , D. Mohnen , T. Kinoshita , N. H. Packer , J. H. Prestegard , R. L. Schnaar , P. H. Seeberger , Cold Spring Harbor Laboratory Press , Cold Spring Harbor (NY) , 4th edn, 2022 , ch. 28

3. Multivalent ligand presentation as a central concept to study intricate carbohydrate–protein interactions

4. Multivalent Carbohydrate-Lectin Interactions: How Synthetic Chemistry Enables Insights into Nanometric Recognition

5. What is the Sugar Code?

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