A synbiotic formulation of <i>Lactobacillus reuteri</i> and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut

A synbiotic formulation of Lactobacillus reuteri and inulin alleviates ASD-like behaviors in a mouse model: the mediating role of the gut–brain axis

Published:2024 Issue:1 Volume:15 Page:387-400
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Wang Chuanchuan¹²,Chen Weixuan¹^ORCID,Jiang Yishan¹,Xiao Xiao¹,Zou Qianhui¹,Liang Jiarui¹,Zhao Yu¹,Wang Qianxu¹,Yuan Tian²³,Guo Rui¹²,Liu Xuebo¹^ORCID,Liu Zhigang¹²^ORCID

Affiliation:

1. Laboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China

2. Northwest A&F University Shenzhen Research Institute, Shenzhen, Guangdong, 518000, China

3. Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Yangling, Shaanxi 712100, China

Abstract

Autism Spectrum Disorder (ASD), a complex neurodevelopmental disorder marked by social communication deficits and repetitive behaviors, may see symptom amelioration through gut microbiota modulation.

Funder

National Natural Science Foundation of China

China Postdoctoral Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D3FO02663A

Reference48 articles.

1. Behavioral neuroscience of autism

2. Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models