Synbiotic therapy with <i>Clostridium sporogenes</i> and xylan promotes gut-derived indole-3-propionic acid and improves cognitive impairments in an Alzheimer's disease mouse model-Reference-Cited by-同舟云学术

Synbiotic therapy with Clostridium sporogenes and xylan promotes gut-derived indole-3-propionic acid and improves cognitive impairments in an Alzheimer's disease mouse model

Published:2024 Issue:15 Volume:15 Page:7865-7882
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Ling¹,Yang Cong¹,Jia Mengzhen¹,Wang Yuhao¹,Zhao Yu¹,Li Qingyuan¹,Gong Jun¹,He Ying¹,Xu Kun²^ORCID,Liu Xuebo¹^ORCID,Chen Xuhui³,Hu Jun³,Liu Zhigang¹⁴^ORCID

Affiliation:

1. Laboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China

2. College of Animal Science and Technology, Northwest A&F University, Yangling, 712100, China

3. Peking University Shenzhen Hospital, Shenzhen, Guangdong, 518004, China

4. Northwest A&F University Shenzhen Research Institute, Shenzhen, Guangdong, 518000, China

Abstract

Targeted synbiotic therapy mitigates cognitive impairment in Alzheimer's disease, emphasizing its potential for addressing neurodegenerative diseases.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO00886C

Reference73 articles.

1. Development of new treatments for Alzheimer’s disease based on the modulation of translocator protein (TSPO)

2. Emerging roles of innate and adaptive immunity in Alzheimer’s disease

3. Alzheimer’s disease: risk factors and potentially protective measures

4. Personalized Gut Mucosal Colonization Resistance to Empiric Probiotics Is Associated with Unique Host and Microbiome Features