IRS-1/PI3K/Akt pathway and miRNAs are involved in whole grain highland barley (Hordeum vulgareL.) ameliorating hyperglycemia of db/db mice-Reference-Cited by-同舟云学术

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IRS-1/PI3K/Akt pathway and miRNAs are involved in whole grain highland barley (Hordeum vulgareL.) ameliorating hyperglycemia of db/db mice

Published:2020 Issue:11 Volume:11 Page:9535-9546
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Deng Na¹²³⁴⁵^ORCID,Guo Ruixue⁶⁷⁸⁵,Zheng Bisheng¹²³⁴⁵,Li Tong⁹¹⁰¹¹¹²,Liu Rui Hai⁹¹⁰¹¹¹²

Affiliation:

1. Overseas Expertise Introduction Center for Discipline Innovation of Food Nutrition and Human Health (111 Center)

2. School of Food Science and Engineering

3. South China University of Technology

4. Guangzhou

5. China

6. School of Food Science

7. Guangdong Pharmaceutical University

8. Zhongshan

9. Department of Food Science

10. Cornell University

11. Ithaca

12. USA

Abstract

The present investigation further unravels the underlying molecular mechanism of WGH on T2DM: IRS-1/PI3K/Akt pathway and related miRNA expression.

Funder

Ministry of Education, China - 111 Project

Natural Science Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO01990A

Reference42 articles.

1. Polysaccharide from Rosa roxburghii Tratt Fruit Attenuates Hyperglycemia and Hyperlipidemia and Regulates Colon Microbiota in Diabetic db/db Mice

2. Assessment of the Phenolic Profiles, Hypoglycemic Activity, and Molecular Mechanism of Different Highland Barley (Hordeum vulgare L.) Varieties

3. Type 2 diabetes

4. Ferulic acid exerts its antidiabetic effect by modulating insulin-signalling molecules in the liver of high-fat diet and fructose-induced type-2 diabetic adult male rat

5. Hypoglycemic effect of whole grain diet in C57BL/KsJ-db/db mice by activating PI3K/Akt and AMPK pathways

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