Photocatalytic difluoromethylarylation of unactivated alkenes <i>via</i> a (hetero)aryl neophyl-like radical migration-Reference-Cited by-同舟云学术

Photocatalytic difluoromethylarylation of unactivated alkenes via a (hetero)aryl neophyl-like radical migration

Published:2022 Issue:29 Volume:20 Page:5712-5715
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lei Ziran¹,Wei Siqi¹,Zhou Liejin¹^ORCID,Zhang Zuxiao¹²^ORCID,Lopez Simon E.²,Dolbier William R.²^ORCID

Affiliation:

1. Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P. R. China

2. Department of Chemistry, University of Florida, Gainesville, FL 32611-7200, USA

Abstract

Photoredox-catalyzed addition of the difluororadical to unactivated alkenes has been found to trigger neophyl-like aryl and heteroaryl migrations which allowed the construction of a diverse series of difluoromethyl ketones.

Funder

Zhejiang Normal University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/OB/D2OB00813K

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