Affiliation:
1. School of Basic Medicine Wannan Medical College Wuhu 241002 China
2. State Key Laboratory of Coordination Chemistry Jiangsu Key Laboratory of Advanced Organic Materials Collaborative Innovation Center of Advanced Microstructures School of Chemistry and Chemical Engineering Nanjing University Nanjing 210023 China
Abstract
AbstractThe difunctionalization of alkenes involving 1,5‐functional group migration strategies for the conversion of versatile and readily available olefins into more structurally complex molecules has been greatly studied. However, the vast majority of the reported reactions rely on strongly oxidizing conditions and oxidizing fluoroalkyl radical reagents. In contrast, few reactions with reduced radical reagents have been reported. This work describes a photo / electroredox catalytic condition for difunctional modification of unactivated olefins via a radical process using IMDN‐Tf reagents with broad substrate scope and excellent tolerance.
Funder
National Natural Science Foundation of China