Identification, isolation, structural characterization, in silico toxicity prediction and in vitro cytotoxicity assay of simeprevir acidic and oxidative degradation products

Author:

Ahmed Rasha M.12345,Fayed Marwa A. A.62785ORCID,El-Behairy Mohammed F.92785ORCID,Abdallah Inas A.102785ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry

2. Faculty of Pharmacy

3. Misr International University

4. Cairo 11341

5. Egypt

6. Department of Pharmacognosy

7. University of Sadat City

8. Sadat City 32897

9. Department of Organic and Medicinal Chemistry

10. Department of Analytical Chemistry

Abstract

Simeprevir is a new direct-acting antiviral drug used for the treatment of chronic hepatitis C.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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