Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor-Reference-Cited by-同舟云学术

Discovery and Development of Simeprevir (TMC435), a HCV NS3/4A Protease Inhibitor

Published:2014-02-14 Issue:5 Volume:57 Page:1673-1693
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rosenquist Åsa¹,Samuelsson Bertil¹,Johansson Per-Ola¹,Cummings Maxwell D.²,Lenz Oliver³,Raboisson Pierre³,Simmen Kenny³,Vendeville Sandrine³,de Kock Herman⁴,Nilsson Magnus⁵,Horvath Andras³,Kalmeijer Ronald³,de la Rosa Guy⁶,Beumont-Mauviel Maria³

Affiliation:

1. Medivir AB, P.O. Box 1086, SE-141 45 Huddinge, Sweden

2. Janssen Research & Development, LLC, Spring House, Pennsylvania 19002, United States

3. Janssen Infectious Diseases BVBA, Beerse 2340, Belgium

4. Galapagos NV Generaal De Wittelaan, L11A3-2800, Mechelen, Belgium

5. AstraZeneca R&D, Mölndal, SE-431 83, Sweden

6. Janssen Global Services, LLC, Titusville, New Jersey 08560, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm401507s

Reference83 articles.

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2. Hepatitis C and liver transplantation

3. Pathogenesis of hepatitis C—associated hepatocellular carcinoma

4. World Health Organization. Hepatitis C, Fact Sheet No. 164. Last updated July 2013.http://www.who.int/mediacentre/factsheets/fs164/en/(accessed May 30, 2013) .

5. Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

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