A designed DNA binding motif that recognizes extended sites and spans two adjacent major grooves-Reference-Cited by-同舟云学术

A designed DNA binding motif that recognizes extended sites and spans two adjacent major grooves

Published:2016 Issue:5 Volume:7 Page:3298-3303
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Rodríguez Jéssica¹²³⁴⁵,Mosquera Jesús¹²³⁴⁵,García-Fandiño Rebeca¹²³⁴⁵^ORCID,Vázquez M. Eugenio¹²³⁴⁵^ORCID,Mascareñas José L.¹²³⁴⁵^ORCID

Affiliation:

1. Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CIQUS)

2. Departamento de Química Orgánica

3. Universidade de Santiago de Compostela

4. 15782 Santiago de Compostela

5. Spain

Abstract

We report the rational design of a DNA-binding peptide construct composed of the DNA-contacting regions of two transcription factors (GCN4 and GAGA) linked through an AT-hook DNA anchor.

Funder

European Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/SC/C6SC00045B

Reference65 articles.

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