Synthesis of 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides and their tautomerism-Reference-Cited by-同舟云学术

Synthesis of 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides and their tautomerism

Published:2018 Issue:40 Volume:8 Page:22351-22360
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lim Felicia Phei Lin¹²³⁴^ORCID,Tan Lin Yuing¹²³⁴^ORCID,Tiekink Edward R. T.⁵⁶⁷³⁴,Dolzhenko Anton V.¹²³⁴⁸^ORCID

Affiliation:

1. School of Pharmacy

2. Monash University Malaysia

3. Selangor Darul Ehsan 47500

4. Malaysia

5. Research Centre for Crystalline Materials

6. School of Science and Technology

7. Sunway University

8. School of Pharmacy and Biomedical Sciences

Abstract

Two complementary pathways for the preparation of N-substituted 3-(5-amino-1H-1,2,4-triazol-3-yl)propanamides were proposed and successfully realized in the synthesis of 20 representative examples.

Funder

Ministry of Higher Education, Malaysia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA04576C

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1. A multidisciplinary study of 3-(β- d -glucopyranosyl)-5-substituted-1,2,4-triazole derivatives as glycogen phosphorylase inhibitors: Computation, synthesis, crystallography and kinetics reveal new potent inhibitors

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3. Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring

4. Synthesis and antimicrobial activity of pyrimidinyl 1,3,4-oxadiazoles, 1,3,4-thiadiazoles and 1,2,4-triazoles

5. Posaconazole liquid vs tablet formulation in lung transplant recipients

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