A microfluidic device for both on-chip dialysis protein crystallization and in situ X-ray diffraction-Reference-Cited by-同舟云学术

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A microfluidic device for both on-chip dialysis protein crystallization and in situ X-ray diffraction

Published:2020 Issue:2 Volume:20 Page:296-310
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Junius Niels¹²³⁴⁵^ORCID,Jaho Sofia¹²³⁴⁵^ORCID,Sallaz-Damaz Yoann¹²³⁴⁵,Borel Franck¹²³⁴⁵^ORCID,Salmon Jean-Baptiste³⁶⁷⁸⁹^ORCID,Budayova-Spano Monika¹²³⁴⁵^ORCID

Affiliation:

1. Université Grenoble Alpes

2. CEA

3. CNRS

4. IBS

5. F-38000 Grenoble

6. Solvay

7. LOF

8. UMR 5258

9. Univ. Bordeaux

Abstract

This paper reports a versatile microfluidic chip developed for on-chip crystallization of proteins through the dialysis method and in situ X-ray diffraction experiments.

Funder

H2020 Marie Skłodowska-Curie Actions

Centre National de la Recherche Scientifique

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/LC/C9LC00651F

Reference46 articles.

1. Serial femtosecond crystallography: A revolution in structural biology

2. Low-dose fixed-target serial synchrotron crystallography

3. Femtosecond X-ray protein nanocrystallography

4. Microfluidics: From crystallization to serial time-resolved crystallography

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