Preparative separation of eight phenolic acids from Echinacea purpurea L. Moench using pH-zone-refining counter-current chromatography and evaluation of their immunomodulatory effects and synergistic potential

Author:

Ma Tianyu12,Dong Hongjing2ORCID,Geng Yanling2,Guo Lanping3,Wang Xiao2ORCID

Affiliation:

1. School of Pharmaceutical Sciences, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China

2. Key Laboratory for Applied Technology of Sophisticated Analytic Instrument of Shandong Province, Shandong Analysis and Test Center, Jinan, 250014, China

3. Resource Center of Chinese Materia Medica, State Key Laboratory Breeding Base of Dao-di Herbs, China Academy of Chinese Medical Sciences, Beijing, 100700, China

Abstract

Eight phenolic acids were isolated from Echinacea purpurea L. Moench using pH-ZRCCC. And the synergistic effect of caffeoyl tartaric acid, feruloyl tartaric acid, and cichoric acid on the inflammation was 94.91%.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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