Electrochemical cycloaddition of hydrazones with cyanamide for the synthesis of substituted 5-amine-1,2,4-triazoles-Reference-Cited by-同舟云学术

Electrochemical cycloaddition of hydrazones with cyanamide for the synthesis of substituted 5-amine-1,2,4-triazoles

Published:2023 Issue:16 Volume:59 Page:2303-2306
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Yang Minghua¹,Jiang Rui²,Mu Yangxiu²,Hong Yu²,Wan Yaya²,Hou Jing²,Tang Dong¹²^ORCID

Affiliation:

1. Department of Chemical and Material Engineering, Quzhou College of Technology, No. 18 Jiangyuan Road, Quzhou 324002, Zhejiang, China

2. Institute of Agricultural Resources and Environment, Ningxia Academy of Agriculture and ForestryScience, Yinchuan, P. R. China

Abstract

An eco-friendly and efficient electrochemical method for the synthesis of 5-amine-1,2,4-triazole derivatives has been developed by employing hydrazones or in situ generation of hydrazones with cyanamide using KI as the catalyst and electrolyte.

Funder

Natural Science Foundation of Ningxia Province

Key Research and Development Program of Ningxia

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D2CC06277A

Reference29 articles.

1. Synthesis and structure–activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors

2. Synthesis and in vitro activity of 1-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-1H-1,2,4-triazol-5-amine and 4-(2,3-dichlorophenyl)-N-(pyridin-3-ylmethyl)-4H-1,2,4-triazol-3-amine P2X7 antagonists

3. Highly Potent Inhibitors of Methionine Aminopeptidase-2 Based on a 1,2,4-Triazole Pharmacophore

4. Synthesis, Antimitotic and Antivascular Activity of 1-(3′,4′,5′-Trimethoxybenzoyl)-3-arylamino-5-amino-1,2,4-triazoles

5. Highly Efficient Cyanoimidation of Aldehydes

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3. Electrochemical Cyclization of Hydrazones and Amidines To Access Trisubstituted 1,2,4-Triazoles;Synlett;2023-04-26

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