Enantioselective catalytic remote perfluoroalkylation of α-branched enals driven by light-Reference-Cited by-同舟云学术

Enantioselective catalytic remote perfluoroalkylation of α-branched enals driven by light

Published:2023 Issue:18 Volume:14 Page:4923-4927
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Balletti Matteo¹,Wachsmuth Tommy¹^ORCID,Di Sabato Antonio¹^ORCID,Hartley Will C.¹,Melchiorre Paolo²^ORCID

Affiliation:

1. ICIQ – Institute of Chemical Research of Catalonia, 43007 Tarragona, Spain

2. Department of Industrial Chemistry ‘Toso Montanari’, University of Bologna, 40136 Bologna, Italy

Abstract

A photochemical organocatalytic method for the enantioselective incorporation of perfluoroalkyl and trifluoromethyl fragments at the remote γ position of α-branched enals is reported.

Funder

Agencia Estatal de Investigación

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC01347B

Reference48 articles.

1. Fluorine in Pharmaceuticals: Looking Beyond Intuition

2. The Many Roles for Fluorine in Medicinal Chemistry

3. Fluorine in medicinal chemistry

4. Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

5. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

Cited by 7 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Challenges and Future Perspectives in Photocatalysis: Conclusions from an Interdisciplinary Workshop;JACS Au;2024-08-08

2. Recent Advances in the Enantioselective Construction of gem‐Difluorinated Carbonyl Moieties;Advanced Synthesis & Catalysis;2024-07-23

3. Perfluoroalkylation Reactions by Electron Donor‐Acceptor Complexes: Recent Advances;ChemPhotoChem;2024-06-04

4. Electrophilic Fluorination of Silyl Dienol Ethers: a General and Selective Access to γ‐Fluoro Enals;Chemistry – A European Journal;2023-12-28

5. Advancements in organocatalysis for radical-mediated asymmetric synthesis: a recent perspective;Chem Catalysis;2023-11