Half-sandwich organometallic Ru and Rh complexes of (N,N) donor compounds: effect of ligand methylation on solution speciation and anticancer activity-Reference-Cited by-同舟云学术

Half-sandwich organometallic Ru and Rh complexes of (N,N) donor compounds: effect of ligand methylation on solution speciation and anticancer activity

Published:2021 Issue:23 Volume:50 Page:8218-8231
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Mészáros János P.¹²³⁴⁵^ORCID,Pape Veronika F. S.⁶⁷⁸⁵⁹,Szakács Gergely⁶⁷⁸⁵¹⁰,Németi Gábor¹²³⁴⁵^ORCID,Dénes Márk¹¹⁷⁸⁵,Holczbauer Tamás¹¹⁷⁸⁵¹²^ORCID,May Nóra V.¹¹⁷⁸⁵^ORCID,Enyedy Éva A.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Inorganic and Analytical Chemistry

2. Interdisciplinary Excellence Centre

3. University of Szeged

4. H-6720 Szeged

5. Hungary

6. Institute of Enzymology

7. Research Centre for Natural Sciences

8. H-1117 Budapest

9. Department of Physiology

10. Institute of Cancer Research

11. Centre for Structural Science

12. Institute of Organic Chemistry

Abstract

Synthesis of organometallic half-sandwich polypyridyl Ru and Rh complexes. Anticancer activity against resistant cancer cell lines and effects of ligand methylation on aqueous chemistry and structure.

Funder

National Research, Development and Innovation Office

Emberi Eroforrások Minisztériuma

Magyar Tudományos Akadémia

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/DT/D1DT00808K

Reference65 articles.

1. Structure–activity relationships for ruthenium and osmium anticancer agents – towards clinical development