Direct benzylic C–H difluoroalkylation with difluoroenoxysilanes by transition metal-free photoredox catalysis-Reference-Cited by-同舟云学术

Direct benzylic C–H difluoroalkylation with difluoroenoxysilanes by transition metal-free photoredox catalysis

Published:2022 Issue:17 Volume:9 Page:4569-4574
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Gui Jing¹²,Sun Manman²,Wu Haijian²,Li Jinshan²,Yang Jianguo¹²,Wang Zhiming¹²^ORCID

Affiliation:

1. Department of Chemistry, Zhejiang Sci-Tech University, Hangzhou, 310018, Zhejiang, China

2. Advanced Research Institute and Department of Chemistry, Taizhou University, Jiaojiang, 318000, Zhejiang, China

Abstract

A visible light promoted direct benzylic C–H difluoroalkylation with difluoroenoxysilanes catalyzed by Na2-eosin Y via a HAT-ORPC pathway has been developed, providing an efficient and atom-economic method for production of α-benzyl-α,α-difluoroketones.

Funder

Natural Science Foundation of Zhejiang Province

Primary Research and Development Plan of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00857B

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