Tuning Benzylic C−H Functionalization of (Thio)xanthenes with Electrochemistry-Reference-Cited by-同舟云学术

Tuning Benzylic C−H Functionalization of (Thio)xanthenes with Electrochemistry

Published:2023-08-19 Issue:16 Volume:28 Page:6139
ISSN:1420-3049
Container-title:Molecules
language:en
Short-container-title:Molecules

Author:

Wang Changji¹,Yang Na²,Li Chao²,He Jian³,Li Hongji²

Affiliation:

1. School of Chemical Engineering, Anhui University of Science and Technology, 168 Taifeng Road, Huainan 232001, China

2. Key Laboratory of Green and Precise Synthetic Chemistry and Applications, Ministry of Education, School of Chemistry and Materials Science, Huaibei Normal University, Huaibei 235000, China

3. Hefei New Online Technology Co., Ltd., Hefei 235000, China

Abstract

Here, we report a tunable electrochemical benzylic C−H functionalization of (thio)xanthenes with terminal alkynes and nitriles in the absence of any catalyst or external chemical oxidant. The benzylic C−H functionalization can be well controlled by varying the electrochemical conditions, affording the specific coupling products via C−C and C−N bond formation.

Funder

National Science Foundation of China

Natural Science Foundation for Distinguished Young Scholars of Anhui Province, China

Publisher

MDPI AG

Subject

Chemistry (miscellaneous),Analytical Chemistry,Organic Chemistry,Physical and Theoretical Chemistry,Molecular Medicine,Drug Discovery,Pharmaceutical Science

Link

https://www.mdpi.com/1420-3049/28/16/6139/pdf

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