Synthetic applications of α,α-difluoroarylacetic acids and salts via decarboxylative functionalization

Abstract

α,α-Difluoroarylacetic acids are stable, inexpensive and readily available building blocks which can be used to access various difluoromethylated aryl motifs via decarboxylative functionalization for the formation of carbon–carbon and carbon-heteroatom (F, O, S) bonds.