Raman micro spectroscopy for in vitro drug screening: subcellular localisation and interactions of doxorubicin
Author:
Affiliation:
1. FOCAS Research Institute
2. Dublin Institute of Technology
3. Dublin 8
4. Ireland
5. Université François-Rabelais de Tours
6. Faculty of Pharmacy
7. 37200 Tours
8. France
Abstract
Raman spectroscopy is used for the localization and tracking of chemotherapeutic drug, doxorubicin, in the intracellular environment of lung cancer cell line. Results show the potential of the technique to monitor the mechanisms of action and response on a molecular level, with subcellular resolution.
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/AN/C5AN00256G
Reference59 articles.
1. Spectropathology for the next generation: Quo vadis?
2. State of the art Raman techniques for biological applications
3. Micro-Raman Spectroscopy Detects Individual Neoplastic and Normal Hematopoietic Cells
4. The use of Raman spectroscopy to differentiate between different prostatic adenocarcinoma cell lines
5. In situCharacterisation of Living Cells by Raman Spectroscopy
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