Catalyst-free synthesis of tetrahydropyrimidines via formal [3+3]-cycloaddition of imines with 1,3,5-hexahydro-1,3,5-triazines
Author:
Affiliation:
1. Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology
2. School of Petrochemical Engineering
3. Changzhou University
4. Changzhou 213164
5. P. R. China
Abstract
A practical and environmentally benign synthesis of poly-substituted tetrahydropyrimidines via formal [3+3]-annulation of imines and 1,3,5-hexahydro-1,3,5-triazines under catalyst-free conditions has been developed.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Jiangsu Province
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/RA/C7RA11973A
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2. Temporal mRNA profiles of inflammatory mediators in the murine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine model of Parkinson’s disease
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