(Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a New Class of Methylenecyclopropane Analogues of Nucleosides:  Synthesis and Antiviral Activity

Author:

Zhou Shaoman1,Kern Earl R.1,Gullen Elizabeth1,Cheng Yung-Chi1,Drach John C.1,Matsumi Shintaro1,Mitsuya Hiroaki1,Zemlicka Jiri1

Affiliation:

1. Department of Chemistry, Developmental Therapeutics Program, Barbara Ann Karmanos Cancer Institute, Wayne State University School of Medicine, Detroit, Michigan 48201-1379, Department of Pediatrics, The University of Alabama School of Medicine, Birmingham, Alabama 35233, Department of Pharmacology, Yale University School of Medicine, New Haven, Connecticut 06510-8066, Department of Biologic and Materials Sciences, School of Dentistry, University of Michigan, Ann Arbor, Michigan 48019-1078, Department of...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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