Soy protein compared with whey protein ameliorates insulin resistance by regulating lipid metabolism, AMPK/mTOR pathway and gut microbiota in high-fat diet-fed mice

Author:

Ji Andong12ORCID,Chen Wei3,Liu Chang4,Zhang Tianyu12ORCID,Shi Runjia12,Wang Xinqi12,Xu Huina12,Li Duo1256ORCID

Affiliation:

1. Institute of Nutrition and Health, Qingdao University, 308 Ningxia Road, Qingdao 266071, China

2. School of Public Health, Qingdao University, Qingdao 266071, China

3. Department of Clinical Nutrition, Chinese Academy of Medical Sciences-Peking Union Medical College, Peking Union Medical College Hospital, Beijing 100730, China

4. Chengyang District Center for Disease Control and Prevention, Qingdao 266108, China

5. Department of Food Science and Nutrition, Zhejiang University, Hangzhou 310058, China

6. Department of Nutrition, Dietetics and Food, Monash University, Melbourne VIC3168, Australia

Abstract

Soy protein was more effective than whey protein in preventing insulin resistance in high-fat diet-fed mice by regulating lipid metabolism, the AMPK/mTOR pathway, and gut microbiota.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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