The vinylogous Mukaiyama aldol reaction (VMAR) in natural product synthesis
Author:
Affiliation:
1. Institute for Organic Chemistry and Centre of Biomolecular Drug Research (BMWZ)
2. Leibniz Universität Hannover
3. 30167 Hannover, Germany
4. Helmholtz Centre for Infection Research (HZI)
5. Braunschweig, Germany
Abstract
This review will provide an overview on the recent developments of polyketide synthesis using the vinylogous Mukaiyama aldol reaction for the construction of advanced intermediates. In general, four different motifs can be constructed efficiently using the recent developments of asymmetric variants of this strategy.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/NP/C3NP70102F
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