Unprecedented synthesis of 1,2,3-triazolo-cinnolinone via Sonogashira coupling and intramolecular cyclization-Reference-Cited by-同舟云学术

Unprecedented synthesis of 1,2,3-triazolo-cinnolinone via Sonogashira coupling and intramolecular cyclization

Published:2018 Issue:26 Volume:16 Page:4840-4848
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kumar Avnish¹²³⁴⁵,Tiwari Dharmendra Kumar⁶²³⁴^ORCID,Sridhar Balasubramanian⁷³⁴,Likhar Pravin R.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Catalysis & Fine Chemicals

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad 500007

4. India

5. Academy of Scientific & Innovative Research (AcSIR)

6. Department of Organic Synthesis and Process Chemistry

7. X-Ray Crystallography Center CSIR-Indian Institute of Chemical Technology

Abstract

An unprecedented copper mediated one-pot sequential synthesis of 1,2,3-triazolo cinnolinone derivatives from 2-halo-phenyl triazoles and terminal alkynes has been reported.

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/OB/C8OB01152D

Reference58 articles.

1. Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors

2. Cinnoline Derivatives with Biological Activity

3. Novel cinnoline-based inhibitors of LRRK2 kinase activity

4. Synthesis and pharmacological evaluation of pyrazolo[4,3-c]cinnoline derivatives as potential anti-inflammatory and antibacterial agents

5. 11H-Pyrido[3′,2′:4,5]pyrrolo[3,2-c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2-c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity

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