11H-Pyrido[3′,2′:4,5]pyrrolo[3,2-c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2-c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity-Reference-Cited by-同舟云学术

11H-Pyrido[3′,2′:4,5]pyrrolo[3,2-c]cinnoline and Pyrido[3′,2′:4,5]pyrrolo[1,2-c][1,2,3]benzotriazine: Two New Ring Systems with Antitumor Activity

Published:2014-11-05 Issue:22 Volume:57 Page:9495-9511
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Parrino Barbara¹,Carbone Anna¹,Muscarella Marina¹,Spanò Virginia¹,Montalbano Alessandra¹,Barraja Paola¹,Salvador Alessia²,Vedaldi Daniela²,Cirrincione Girolamo¹,Diana Patrizia¹

Affiliation:

1. Dipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche (STEBICEF), Università di Palermo, Via Archirafi 32, 90123 Palermo, Italy

2. Dipartimento di Scienze del Farmaco, Università di Padova, Via F. Marzolo 5, 35121 Padova, Italy

Funder

Ministero dell'Istruzione, dell'Università e della Ricerca

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm501244f

Reference61 articles.

1. Cinnoline Derivatives with Biological Activity

2. Development of novel benzotriazines for drug discovery

3. Substituted dibenzo[ c,h ]cinnolines: topoisomerase I-targeting anticancer agents

4. Synthesis and biological evaluation of 2,7-Dihydro-3H-dibenzo[de,h]cinnoline-3,7-dione derivatives, a novel group of anticancer agents active on a multidrug resistant cell line

5. 11H-Isoquino[4,3-c]cinnolin-12-ones novel anticancer agents with potent topoisomerase I-targeting activity and cytotoxicity

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