Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors-Reference-Cited by-同舟云学术

Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors

Published:2012-03 Issue:6 Volume:22 Page:2262-2265
ISSN:0960-894X
Container-title:Bioorganic & Medicinal Chemistry Letters
language:en
Short-container-title:Bioorganic & Medicinal Chemistry Letters

Author:

Hu Essa,Kunz Roxanne K.,Rumfelt Shannon,Chen Ning,Bürli Roland,Li Chun,Andrews Kristin L.,Zhang Jiandong,Chmait Samer,Kogan Jeffrey,Lindstrom Michelle,Hitchcock Stephen A.,Treanor James

Publisher

Elsevier BV

Subject

Organic Chemistry,Clinical Biochemistry,Drug Discovery,Pharmaceutical Science,Molecular Biology,Molecular Medicine,Biochemistry

Reference29 articles.

1. Isolation and characterization of a dual-substrate phosphodiesterase gene family: PDE10A

2. Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use

3. Cyclic nucleotide phosphodiesterases as targets for treatment of haematological malignancies

4. Biochemistry and Physiology of Cyclic Nucleotide Phosphodiesterases: Essential Components in Cyclic Nucleotide Signaling

5. Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

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