Fluorescent and electrochemical detection of nuclease activity associated with <i>Streptococcus pneumoniae</i> using specific oligonucleotide probes-Reference-Cited by-同舟云学术

Fluorescent and electrochemical detection of nuclease activity associated with Streptococcus pneumoniae using specific oligonucleotide probes

Published:2024 Issue:4 Volume:149 Page:1289-1296
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Goikoetxea Garazi¹²³,Akhtar Khadija-Tul Kubra¹⁴⁵,Prysiazhniuk Alona¹⁴⁵⁶,Borsa Baris A.¹⁴⁵,Aldag Mehmet Ersoy⁷,Kavruk Murat⁸^ORCID,Ozalp Veli C.⁹,Hernandez Frank J.¹⁴⁵^ORCID

Affiliation:

1. Nucleic Acids Technologies Laboratory (NAT-Lab), Linköping University, 58185, Sweden

2. Department of Cellular Biology and Histology, Faculty of Medicine and Odontology, University of Basque Country (UPV/EHU), 48940, Spain

3. SOMAprobes SL. Donostia, 20009, Spain

4. Wallenberg Center for Molecular Medicine, Linköping University, 58185, Sweden

5. Department of Physics, Chemistry and Biology, Linköping University, 58185, Sweden

6. Taras Shevchenko National University of Kyiv, Kyiv, Ukraine

7. Prof. Dr A. Ilhan Özdemir State Hospital, Giresun, Turkey

8. Department of Medical Biology, School of Medicine, Istanbul Aydin University, Istanbul, Turkey

9. Department of Medical Biology, Atilim University, 06830, Ankara, Turkey

Abstract

A chemically modified oligonucleotide has been engineered to specifically target and interact with the nucleases associated with S. pneumoniae, enabling efficient detection of the bacteria through fluorescence and electrochemical biosensors.

Funder

Vetenskapsrådet

Knut och Alice Wallenbergs Stiftelse

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AN/D3AN01532G

Reference33 articles.

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5. Severe community-acquired Streptococcus pneumoniae bacterial meningitis: clinical and prognostic picture from the intensive care unit

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