Harnessing the intrinsic photochemistry of isoxazoles for the development of chemoproteomic crosslinking methods-Reference-Cited by-同舟云学术

Harnessing the intrinsic photochemistry of isoxazoles for the development of chemoproteomic crosslinking methods

Published:2022 Issue:65 Volume:58 Page:9116-9119
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Lougee Marshall G.¹^ORCID,Pagar Vinayak Vishnu¹²^ORCID,Kim Hee Jong³^ORCID,Pancoe Samantha X.¹,Chia W. Kit²^ORCID,Mach Robert H.²^ORCID,Garcia Benjamin A.³^ORCID,Petersson E. James¹^ORCID

Affiliation:

1. Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

2. Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, 19104, USA

3. Biochemistry and Molecular Biophysics Graduate Group, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA

Abstract

The intrinsic photochemistry of the isoxazole, a common heterocycle in medicinal chemistry, can offer an alternative to existing strategies using more perturbing, extrinsic photo-crosslinkers.

Funder

National Institutes of Health

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/CC/D2CC02263J

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