Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search-Reference-Cited by-同舟云学术

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Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search

Published:2023-03-29 Issue:4 Volume:25 Page:704-719
ISSN:1536-1632
Container-title:Molecular Imaging and Biology
language:en
Short-container-title:Mol Imaging Biol

Author:

Janssen Bieneke,Tian Guilong,Lengyel-Zhand Zsofia,Hsieh Chia-Ju,Lougee Marshall G.,Riad Aladdin,Xu Kuiying,Hou Catherine,Weng Chi-Chang,Lopresti Brian J.,Kim Hee Jong,Pagar Vinayak V.,Ferrie John J.,Garcia Benjamin A.,Mathis Chester A.,Luk Kelvin,Petersson E. James,Mach Robert H.^ORCID

Funder

National Institute of Neurological Disorders and Stroke

National Institute on Aging

Michael J. Fox Foundation for Parkinson's Research

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Link

https://link.springer.com/content/pdf/10.1007/s11307-023-01814-9.pdf

Reference53 articles.

1. Henderson MX, Trojanowski JQ, Lee VM (2019) α-Synuclein pathology in Parkinson’s disease and related α-synucleinopathies. Neurosci Lett 709:134316

2. Seibyl JP (2022) Alpha-synuclein PET and Parkinson disease therapeutic trials: ever the twain shall meet? J Nucl Med 63(10):1463–1466

3. Pancoe SX et al (2022) Effects of mutations and post-translational modifications on α-synuclein in vitro aggregation. J Mol Biol 434(23):167859

4. Gibb W, Lees A (1988) The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson’s disease. J Neurol Neurosurg Psychiatry 51(6):745–752

5. Gibb W, Lees A (1989) The significance of the Lewy body in the diagnosis of idiopathic Parkinson’s disease. Neuropathol Appl Neurobiol 15(1):27–44

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3. A Novel Brain PET Radiotracer for Imaging Alpha Synuclein Fibrils in Multiple System Atrophy;Journal of Medicinal Chemistry;2023-08-31

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