Rational design and synthesis of novel 2-(substituted-2H-chromen-3-yl)-5-aryl-1H-imidazole derivatives as an anti-angiogenesis and anti-cancer agent-Reference-Cited by-同舟云学术

Rational design and synthesis of novel 2-(substituted-2H-chromen-3-yl)-5-aryl-1H-imidazole derivatives as an anti-angiogenesis and anti-cancer agent

Published:2014 Issue:99 Volume:4 Page:56489-56501
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Gudipudi Gopinath¹²³,Sagurthi Someswar R.⁴²³,Perugu Shyam⁵²³,Achaiah G.⁶⁷⁸⁹,David Krupadanam G. L.¹²³

Affiliation:

1. Department of Chemistry

2. Osmania University

3. Hyderabad, India 500 007

4. Department of Genetics

5. Department of Biochemistry

6. Medicinal Chemistry Division

7. University College of Pharmaceutical Sciences

8. Kakatiya University

9. Warangal, India 500 009

Abstract

Based on the earlier proven pharmacophore analogues of cancer a novel 2-(substituted-2H-chromen-3-yl)-5-aryl-1H-imidazoles were rationally designed, synthesized and used for competitive biological activity against cancer cell lines.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA09945A

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