C(sp<sup>2</sup>)–H cyclobutylation of hydroxyarenes enabled by silver-π-acid catalysis: diastereocontrolled synthesis of 1,3-difunctionalized cyclobutanes-Reference-Cited by-同舟云学术

C(sp²)–H cyclobutylation of hydroxyarenes enabled by silver-π-acid catalysis: diastereocontrolled synthesis of 1,3-difunctionalized cyclobutanes

Published:2023 Issue:36 Volume:14 Page:9696-9703
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Tang Lei¹^ORCID,Huang Qi-Nan¹^ORCID,Wu Feng¹^ORCID,Xiao Yuanjiu¹^ORCID,Zhou Jin-Lan¹^ORCID,Xu Tong-Tong¹^ORCID,Wu Wen-Biao¹^ORCID,Qu Shuanglin¹^ORCID,Feng Jian-Jun¹^ORCID

Affiliation:

1. State Key Laboratory of Chemo/Biosensing and Chemometrics, Advanced Catalytic Engineering Research Center of the Ministry of Education, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan 410082, P. R. China

Abstract

A carbophilic silver Lewis acid catalyzes polar strain-release ring-opening of BCBs with hydroxyarenes to afford 1,1,3-trisubstituted cyclobutanes in high yields and excellent chemo- and diastereoselectivity.

Funder

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03258B

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